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Anti -OB Cadherin Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012250
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HMR
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

OB Cadherin rabbit polyclonal antibody

Protein full name

Cadherin-11

Synonyms

OSF-4, Cdh11, Cad-11, Osteoblast cadherin, OB-cadherin

Immunogen

Recombinant protein corresponding to Mouse OB Cadherin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

88 kDa

Observed MW.

120 kDa

Uniprot ID

P55287, P55288




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, uterus




Background


This gene encodes a type II classical cadherin from the cadherin super family, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-11 (OB-Cadherin) is a marker of the loosely connected and migratory cellular elements of the mesenchyme.  Expression of this particular cadherin in osteoblastic cell lines, and its up regulation during differentiation, suggests a specific function in bone development and maintenance. Recently, Cadherin-11 mRNA and protein were found to be expressed in most invasive breast cancer cell lines tested but not in non-invasive cell lines, suggesting that Cadherin-11 may be a marker for aggressive, invasive tumor subsets.




Images


Picture 1.png

Western blot analysis of OB-Cadherin (GB111278) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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