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Anti -CD3 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101771
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

CD3 rabbit polyclonal

Protein full name

T-cell surface glycoprotein CD3 epsilon chain

Synonyms

CD3E, IMD18, T3E, TCRE, CD3e molecule

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD3

Isotype

IgG

Purity

Affinity purification

Predicted molecular

23 kDa

Observed molecular

22 kDa

Subcellular location

Cell membrane

Uniprot ID

P22646



Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

thymus, lymph node

IHC

Human, Mouse, Rat

1: 700-1: 1400

lymph node, tonsil, spleen

IF

Human, Mouse, Rat

1: 700-1: 1400

tonsil, spleen




Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.





Images



Western blot analysis of CD3 (GB111337) 

at dilution of 1: 1000


Western blot analysis of CD3 (GB111337) 

at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded human tonsil using 

CD3 (GB111337) at dilution of 1: 700


Immunohistochemistry analysis of paraffin-embedded mouse spleen using 

CD3 (GB111337) at dilution of 1: 700


Immunohistochemistry analysis of paraffin-embedded rat spleen using 

CD3 (GB111337) at dilution of 1: 700


Immunohistochemistry analysis of paraffin-embedded rat lymph node using 

CD3 (GB111337) at dilution of 1: 700


Immunohistochemistry analysis of paraffin-embedded rat lymph using CD3 (GB111337) at dilution of 1: 1400

Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using 

CD3 (GB111337) at dilution of 1: 700

Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using 

CD3 (GB111337) at dilution of 1: 700




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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